Lois Smith

as Elizabeth Crawford (voice)

as Trudie Ferreira

as Helen

as Delores Feinn

as Beverly

as Betty

as Upshur 'Maw' Clampette

as Iris Lefferts

as Doris 'Mama' Boone

as Aunt Butch

as Harper Pitt

as The Grande Dame

as Mimi Waldenstock

as Deirdre 'Dippy' Jones

as Wrong Nana

as Sister Sarah Joan

as Marjorie

as Miriam

as Mrs. Glenn

as Reverend Ethel Landry

as Mrs. Hanson

as Belinda Lacroix

as Margaret Conlon

as Self

as The Youngest Daughter (later)

as Lucy Game

as Claire

as Dolores

as Betty Turner

as Ruth

as Aunt Mel

as Mom

as Mrs. Portman

as Lois Blair

as Adele Stackhouse

as Belle

as Abby

as Elsie

as Dr. Imberman

as Helen Bessolo

as Inge (as an older woman)

as Self

as Mrs. Dickerson

as Ellie Silverstein

as Allison Scavo

as Rose Sinclair

as Reverend Anna Howard Shaw

as Helen

as Fannie

as Helen Rounds

as Dr. Iris Hineman

as Lucy Thompson

as Betty Bennett

as Mother

as Mother

as Helen Jackson

as Ginger

as Rebecca Tolliver

as Miss Maude

as Mrs. Ferriter

as Mary Beth Berluti

as Libby

as Luluna

as Aunt Meg

as Helen's Mother

as Sophia

as Madge Wallace Gates

as Mildred Mancini

as Gracie

as Orna

as Moira

as D-Fens' Mother

as Lou Wheaton

as Dianne's Mother

as voice

as Lureen

as Mrs. Bell

as Mama Threadgoode

as Alice Todd

as Margaret

as Ma Joad

as (voice)

as Brontë's Mother

as Eunice Varick

as Self

as (voice)

as Mrs. Nelson, Mardukas's Friend

as Martha

as Sara

as Sarah

as Mary Neal

as Marie Ganucci

as Dorothy Hermes

as Helen Giles

as Mrs. Prescott

as Mare Spofford

as Clara

as Mrs. Carnahan

as Kathy

as Cornelia

as Mrs. Axman

as Sara

as Anita Cunningham

as Elinore

as Woman (segment "Talk to Me Like the Rain and Let Me Listen")

as Partita Dupea

as Jane Aldridge

as Evelyn

as Libby Clayton

as Esther Terranova

as Dana

as Lucy Brown

as Hilda

as Dawn Garrison

as Self - Nominee

as Self - Nominee/Performer

as Spurs O'Brien

as Anne

as Jeannie

as Jenny Musgrave

as Lisa Molloy